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Abstract Detail


Oyedapo, Ololade [1], Agbedahunsi, Joseph Morounfolu [2], Illoh, Halbert Chukwuma [3], Akinloye, Akinwumi [4].

Comparative Bark Anatomy of Three Khaya species used in Nigeria as antisickling agent.

Khaya belongs to the family Meliaceae. The three species found in Nigeria are the genus represented by three species cuz Khaya selegalensis, Khaya grandifoliola and Khaya ivorensis. Khaya have been found to be very useful in treatment of arrays of diseases in Nigeria among which are malaria and sickle cell disease. The three species are referred to as Oganwo in Yoruba tribe and are used by Traditional Medical Practitioners (TMC) in treating sickle cell disease. The TMC find it difficult to identify hence the study. Comparative bark anatomy and macerates of the three species was carried out to identify and describe distinctive anatomical characters that could possibly be used to delimit the taxa. Transverse and longitudinal section with macerate of stem and root bark were made.Characteriatic similarity and disparity in the tissue arrangements as well as cell inclusions were noted for description and delimitation. The antisickling activities of the bark of the three species and chromatographic fingerprints of the most active extracts were carried out, the proximate end elemental analysis were also carried out.The three Khaya species had essentially same anatomical features. The cuticle shape and type, epidermal cell shape and cell inclusions reveal some similarities. The study revealed the cuticle were striated, the shape of the cuticle ranges from circular, oval, polygonal, cylindrical elongated cell. Sclereids are present and prominent. However there were characters that were species specific in the number of outer bark cell layers, cuticle thickness, numerousity of crystal present into he cell. The presence of stalloid crystal that is inthe cell of Khaya grandifoliola distinguished it from two other species. The three Khaya species has antisickling effect for reversal and inhibition of sickle cell and contain essential elements necessary for good growth of sickle cell patients. Microscopic study of the bark of the three species revealed that there were distinctive diagnostic features that can be used in solving the identification problem of species of Khaya studied from one another.

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1 - Obafemi Awolowo University, Drug Research And Production Unit , Faculty Of Pharmacy , Ile Ife, OS, 23401, Nigeria
2 - Obafemi Awolowo university , Drug Research and Production , Department of Drug Research and Production Unit , Ile-Ife, Osun, 23401, Nigeria
3 - Obafemi Awolowo university , Department of Botany , Department of Botany, Ile-Ife, Osun, 23401, Nigeria
4 - Obafemi Awolowo University, Botany, Ile-Ife, Osun State, Nigeria, Botany Department, Obafemi Awolowo University, Ile-Ife., OS, 234, Nigeria


Presentation Type: Oral Paper
Session: ETH1, Ethnobotany
Location: San Luis 2/Starr Pass
Date: Tuesday, July 30th, 2019
Time: 8:15 AM
Number: ETH1002
Abstract ID:94
Candidate for Awards:None

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